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Type 2 Diabetes

Reversible for some, lifelong for others — but always manageable.

Type 2 diabetes is a chronic condition where insulin resistance and, eventually, reduced insulin production raise blood glucose. Long-term complications include eye, kidney, nerve, and heart damage, but tight early control dramatically reduces risk.

Causes & risk factors

  • Genetics and family history
  • Overweight, especially abdominal fat
  • Physical inactivity
  • Age over 45 (though rising in younger adults)
  • Gestational diabetes in prior pregnancy
  • PCOS and other insulin-resistance states

Symptoms

  • Frequent urination, especially at night
  • Increased thirst and hunger
  • Unexplained weight loss
  • Fatigue and slow-healing wounds
  • Blurred vision
  • Tingling in hands or feet

How it's diagnosed

  • HbA1c ≥ 6.5% on two occasions
  • Fasting glucose ≥ 126 mg/dL on two occasions
  • Random glucose ≥ 200 mg/dL with symptoms
  • Oral glucose tolerance test in borderline cases
  • Baseline kidney, lipid, and liver function

Evidence-based treatment

  • Weight loss — 5-10% can dramatically improve control
  • Mediterranean-style or low-carb diet
  • Metformin as first-line drug
  • GLP-1 agonists (semaglutide, liraglutide) for weight + glucose
  • SGLT2 inhibitors for heart and kidney protection
  • Insulin when oral agents are insufficient

Prevention

  • Maintain healthy weight
  • Daily movement — walks after meals
  • Reduce refined carbs and sugary drinks
  • Annual HbA1c from 35, earlier if high risk

Related symptoms

Type 2 Diabetes — FAQ

Can type 2 diabetes be reversed?

A meaningful minority of patients can achieve non-diabetic HbA1c values with substantial weight loss, especially if the diagnosis is recent. Ongoing lifestyle maintenance is essential.

What HbA1c should I aim for?

Under 7% is the standard adult target. Younger patients without complications often aim for under 6.5%; older patients or those with cardiovascular disease may accept 7.5-8%.